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KMID : 0383819780250010022
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Tuberculosis and Respiratory Diseases
1978 Volume.25 No. 1 p.22 ~ p.25
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A case of SIADH with Pulmonary Tuberculosis and Tuberculous Meningitis
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박중진/Chong Jin Park
백남종/이오정/박성학/변해원/Nam Jong Paik/O Jung Lee/Sung Hak Park/Hae Won Byun
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Abstract
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It was well known that the syndrome of inapproprate secretion of antdiuretic hormone
(SIADH) has been associated with many pulmonary diseases, cancers, diseases of the
central nervous system, and drugs. But there were a few reports of the SIADH
associated with pulmonary tuberculosis and tuberculous meningitis in spite of its high
prevalence rate in Korea.
We experienced a case of the SIADH associated with pulmonary tuberculoss with
tuberculous meningitis. Before the start of therapy, his serum sodium concentration was
127 mEq/L, serum osmolality 265 mOsm/㎏., urinary sodium concentration 310 mEq/day,
and the urine osmolality 590 mOsm/㎏. The creatinine clearance and intravenous insulin
tolerance test for adrenal reserve function was normal. No other causes of this SIADH
were apparent. Neverthless, the most probable underlying cause of SIADH in this case
wart pulmonary tuberculosis combined with tuberculous meningitis. This was frilly
recovered after combined antituberculous therapy.
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